FAQ

“A syndrome is a recognizable complex of symptoms and physical findings which indicate a specific condition for which a direct cause is not necessarily understood. Thus in practice doctors refer to the infamous “viral syndrome” as such because of the uncertainty regarding the legion of viral agents that is causing the illness. Once medical science identifies a causative agent or process with a fairly high degree of certainty, physicians may then refer to the process as a disease, not a syndrome. Mucocutaneous lymph node syndrome became Kawasaki syndrome which in turn metamorphosed into Kawasaki disease; the latter is properly a disease, no longer a syndrome, by virtue of its clearly identifiable diagnostic features and disease progression, and response to specific treatment.”

https://pmc.ncbi.nlm.nih.gov/articles/PMC1480257

PSS might be the same condition as PSSD (post SSRI sexual dysfunction). Assuming it is, PSS is a more appropriate term that doesn’t make emphasis on sexual symptoms.

Diagnostic Criteria Mismatch: FND requires positive clinical signs of functional incompatibility (e.g., symptoms that vary with attention, like Hoover’s sign or distractible tremors). In Post SSRI Syndrome, neurological evaluations show consistent genital sensory loss (e.g., pinprick or von Frey hair abnormalities) without these functional signs—tests often indicate normal peripheral neurophysiology but suggest central (brain-level) impairment from drug effects. This points to a persistent biological alteration, not the reversible network dysfunction of FND.